第四十八章 开发癌症疫苗

教学资料

• 教学参考
• 课件
• 小清爱提问：人工智能如何助力开发癌症疫苗？ [1]

扩展阅读

• WHO: 苗如何发挥作用? {https://www.who.int/zh/news-room/feature-stories/detail/how-do-vaccines-work}
• 维基百科：免疫系统 [2]
• 维基百科：免疫疗法[3]

视频展示

• 疫苗的历史：人类与病毒之间的史诗级战役，最终谁赢了？ [4]
• 细胞免疫 [5]

开发者资源

• Source Code for paper [6] [7]

高级读者

• Hu Z, Ott P A, Wu C J. Towards personalized, tumour-specific, therapeutic vaccines for cancer[J]. Nature Reviews Immunology, 2018, 18(3): 168-182. [8]
• Andreatta, M. & Nielsen, M. Gapped sequence alignment using artificial neural networks: application to the MHC class I system. Bioinformatics 32, 511–517 (2016).
• Calling cancer’s bluff with neoantigen vaccines， https://www.nature.com/articles/d41586-017-08706-3
• Ngoc Hieu Tran, Rui Qiao, Lei Xin, Xin Chen, Baozhen Shan，Ming Li， Personalized deep learning of individual immunopeptidomes to identify neoantigens for cancer vaccines， Nature Machine Intelligence, 2, pages764–771(2020) [9]